The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App 
Professionals >> Visit The Body PROThe Body en Espanol
Ask the Experts About

Mental Health and HIVMental Health and HIV
Rollover images to visit our other forums!
Recent AnswersAsk a Question
  • Email Email
  • Glossary Glossary

Which SNRI increases dopamine the most?

Feb 3, 2013

Which SNRI out of Effexor and Cymbalta increases dopamine the most and has the most/best effect on dopamine? Also, are there any tables or research on this anywhere?

Response from Dr. Fawcett

Thanks for writing. SNRIs (serotonin-norepinephrine reuptake inhibitors) are so-called dual-action drugs that are used to treat major depression and other mood disorders. They are called dual-action because they work on those two specific neurotransmitters.

There is no simple answer to your question. First, the effectiveness of these drugs stems from the impact on both norepinephrine and dopamine, not just the latter. Second, the impact on dopamine reuptake can be dependent on dosage. Effexor, for example, has little effect on dopamine reuptake at lower doses but it increases at higher doses.

Speak with your physician to select the best medication for your symptoms.



Does drinking Chinese tea (Gunpowder or Green Tea) affect HIV treatment?
Hepatitis C

  • Email Email
  • Glossary Glossary

 Get Email Notifications When This Forum Updates or Subscribe With RSS



This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.

Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.

Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint