|Still depressed after interferon
Aug 14, 2012
I recently cleared HEP C (and am HIV). I have had good health but the depression from the interferon has not subsided even after 6 months. I am angry all the time and I know it is depression. I am also medicated for bipolar disorder with lithium, Prozac 100mg a day and Clozapam 4mg a day with 1 7.5 vicoprofen a day. I have no viral load at all and a rising T cell count. I just feel tired and hopeless after 25 years. I am very negative and everyone seems to want to get away from me. My memory is terrible and I almost knocked my eye out with a knife. I have secondary Glaucoma now after months of no vision. I was not this way before the awful year of interferon. I should be happy but I'm becoming more afraid of people and they seem more hostile which is probably my projection.
| Response from Dr. Fawcett
Thanks for writing and congratulations on clearing the Hep C. Serious depression is quite common with the use of interferon - I'm sorry you have had this experience. You have some complex issues: depression, bipolar disorder, and now another serious medical condition, Glaucoma, which must be affecting your mood.
While the Prozac may be helping your depressive symptoms, I think it would be prudent, if possible, to get a thorough assessment by a psychopharmacologist, someone who specializes in the interaction of various psychotropic medications. There might be a more effective antidepressant and your perception of hostility in others could be a bipolar symptom which is not well-controlled. Combining those medications, along with anti-anxiety and a pain medication, can have a synergistic effect. Sometimes medications are added over time. It would probably be useful to have your doctors take a step back and look at all your medications to see if it's the best possible combination for you at the present time.
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