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Atripla Advise

Jan 28, 2008

Hi Dr. Horwath,

I am writing this to you and see if you can post this, I've been on Atripla for jus a bit over two years, I was told by my ID Dr. that the Nervous System side effects due to the Sustiva in Atripla will fade away after a few weeks into treatment and this is not the case, I have talked to other people that also are on Atripla and they still have these side effects, so I don't know if these are isolated cases, but the NS side effects by the Sustiva in Atripla they stay with you, some times you have them more intense some times a bit less. A good way to relieve these symptoms is take other medications like Restoril 30 mg to help you keep asleep at night and for the anxiety Xanax or clonazepan it helps a lot, also if you have access to good health care and medications take Marinol, it has a very calming effect and does take all of the bothersome side effects of the Efavarenz in Atripla, I don't know if you can post this but the ones I know and myself we follow these treatment and it helps you a lot, other is to have someone to talk at all times... Best regards...

Response from Dr. Horwath

Yes, efavirenz (Sustiva), which is a component of Atripla, has significant central nervous system side effects. Oftentimes, these side effects are transient and only last several weeks. However, in some cases, such as yours, the side effects may persist. Insomnia and unusual dreams are frequent side effects, for example.

Thank you for sharing your experiences.

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