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| HIV DEMENTIA Jul 6, 2004 Which drugs with good CNS penetration would these be? I am currently taking viramune/epivir/zerit? Also are the alzheimer drugs beneficial? Thank You |
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Response from Dr. Horwath
There are several antiretroviral drugs with known good CNS penetration. These include zidovudine (AZT, Retrovir), stavudine (Zerit), lamivudine (Epivir), nevirapine (Viramune), and indinavir (Crixivan). In general, the protease inhibitors do not have good CNS penetration, with the exception of indinavir. Of the 3 meds you are taking, they are all good penetrators. There have been no studies with drugs currently used to treat Alzheimer's disease. | |||||||||
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