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Correlation between ARS and AIDS progression?
Feb 1, 1998

I wonder if there are studies analyzing whether people who get severe acute retroviral syndrome right after infection with HIV progress faster to AIDS, or if people who don't experience ARS are slow progressors. Is there any correlation at all between ARS and AIDS that we know of?

Response from Dr. Gallant

There does appear to be a correlation between the severity of the acute retroviral syndrome, the degree of viral load elevation during that syndrome, and the subsequent immunologic and virologic "set-points" following recovery.

In other words, if ARS is bad and the viral load is very high, when it's over you may be left with a lower CD4 count and a higher viral load than someone who had a milder case of ARS, and that in turn could affect your subsequent rate of progression.

JG



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