Trivicay and odefsey
Sep 14, 2017
Response from Dr. Young
Hello and thanks for posting.
While you've not said exactly why your doctor has decided to switch your treatment, there's no particular reason why the combination of Odefsey (tenofovir alafenamide/emtricitabine/rilpirivine) and Tivicay (dolutegravir) couldn't be given together. Indeed, there are large clinical trials supporting the use rilpirivine and dolutegravir as two-drug treatment for people who have viral suppression on three drug treatment (called the SWORD clinical trials, discussed in this article on TheBodyPro.com); a combo pill of these two drugs is likely to available in the near future. There are no negative drug-drug interactions between the four antiretroviral medications in the Odefsey or Tivicay; though the former requires that the meds be taken with a meal and there are other potential drug-drug interactions (especially with stomach acid lowering medications) that you and your provider should be mindful of.
What is of interest to me is what has led your doctor to offer this somewhat unusual 4 drug combination. Is there a history of drug resistant virus? For most people, having three (and as noted above, for some, two) active drugs in the treatment regimen is sufficient to maintain viral suppression (and all the good health outcomes that go with that).
I hope that's helpful, BY
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Odds Of Getting HIV Vaginal Sex Condom Broke
- Flaky Skin Could I Have Acute HIV Infection
- Black Spots After Anal Fingering Worried I Have HIV
- Hpv After Swallowing Sperm Worried I Have HIV
- White Discharge After Vaginal Sex With Condom Does It Mean I Have HIV
- Can You Get Genital Warts From Sharing Razors Or Drinks?
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.