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HIV1 HIV 2 & MDR TB
Dec 18, 2014

DEAR DOCTOR, MY FRIEND HAS BEEN DIAGNOSED WITH CO INFECTION OF HIV 1, HIV 2 AND MULTI DRUG RESISTANT TUBERCULOSIS ON JULY 14. HIS AGE IS 62 YEARS AND WEIGHT WAS 45 KG IN JULY 14 AND HEIGHT IS 5FT 2INCHES. HIS CD COUNT AT THE TIME OF DIAGNOSIS WAS 95. HE IS ON MEDICATION FOR MDR TB FOR THE LAST 4 MONTHS. NOW HE HAS REGAINED 5 KG AND WEIGHS 50 KG. WE HAVE CHECKED HIS CD COUNT ON 10TH NOVEMBER AND IT WAS SHOWING 220. HE HAS STARTED ART ON 10TH NOVEMBER. BUT ON 4TH DECEMBER HE WAS DIAGNOSED WITH JAUNDICE AND HENCE THE TB MEDICATION WAS STOPPED. NOW, HE IS THROWING UP MOST OF HIS FOOD AND HENCE LOST 5 KGS. HE IS STABLE RIGHT NOW. CAN YOU PLEASE TELL ME HOW MANY MORE YEARS/ MONTHS APPROXIMATELY HE CAN LIVE IF HE IS EATING HEALTHILY AND TAKING MEDICATIONS ON TIME. PLEASE GUIDE.

Response from Dr. Young

Hello and thanks for posting.

Sorry to learn about your friend's medical challenges.

It's difficult to predict prognosis via the limited information in these types of fora, but it sounds like he's had a good initial response to his HIV treatment (with doubling of his CD4 count to numbers outside of the AIDS-defining levels). HIV-2 tends to be less of an acute issue and treated by many of the HIV-1 medications.

It's also relevant that he has tuberculosis co-infection as this is the leading cause of complications and death worldwide among people living with HIV. There are issues with overlapping side effects and drug-drug interactions between HIV and TB drugs and it sounds as if one of these problems is going on. Usually, these can be navigated, though the process can take time.

Knowing that he's able to eat healthy and stay adherent to his multiple medications is very reassuring to me. Assuming that his healthcare team can figure this out and that his TB is eventually resolved, it's entirely possible to have a normal quality and quantity of life- such is happening in a number of communities around the world.

I hope that helps, BY


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