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Jun 14, 2014

Hello doctor young,am from Uganda,one day my girl friend went for vacation in south Africa and when she came back stupidly we had unprotected sex for two consecutive nights,then I requested her to for HIV testing,unfortunately the results were positive and I was advised by my doctor to take pep and it was astripla but one day I read about it as not being recommended and the virus is resistant to it and its now three weeks after the doze and am having fatigue and headache.should it be HIV worried doctor help me

Response from Dr. Young

Hello and thanks for posting.

There is some regional differences in which PEP regimens are recommended. The current (and perhaps somewhat dated) World Health Organization guidelines generally recommend two NRTI medications (such as the tenofovir/FTC in Atripla). For low income countries, a third medication is usually reserved for suspected cases of drug resistance- and in this case, generally a protease inhibitor is used.

There's nothing wrong, per se, with using Atripla, it's just that the side effects of the efavirenz can be a problem for people and here in the US, viral resistance is relatively significant.

Your symptoms are very non-specific and not the hallmark of HIV infection.

Hope that helps, BY

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