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considering Pep
May 1, 2014

1) i had unprotected anal sex with a positive man who's viral count is at zero (receiving and giving) and he has never missed a day of medication; he told me the chances of transmission are close to impossible especially since he did not ejaculate inside. But now i am having second thoughts. Should i go on it? 2) what are the serious side effects 3)how long do you take PEP a week(s), month?

Response from Dr. Young

Hello and thanks for posting your question about PEP.

1) Having an undetectable viral load dramatically reduces the risk of HIV transmission. In one very large recent study, after about 45,000 sex events (about 15,000 without condoms), there were no HIV transmissions among couples where the positive partner had an undetectable viral load. The decision to go on PEP at this point is dependent on many additional factors- how much do you trust the statement of treatment status?

2,3) PEP is very effective in reducing risk of HIV infection if started within 72 hours of exposure- and is usually very well tolerated- provided that current, and modern regimens are used. The newest recommendations from the New York State Health Department AIDS Institute call for the use of Truvada + Isentress for 4 weeks. This regimen is remarkably well tolerated and rarely results in significant side effects or toxicity.

Hope that's helpful, BY



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