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3TC/AZT to 3TC/TDF to 3TC/AZT again
Apr 12, 2014

Hi,

Here in the Philippines, some treatment hubs are experiencing shortage in Tenofovir meds.

In effect, those who experienced incompatibility with Zidovudine (AZT) and were switched to Tenofovir (TDF) had to switch back to AZT. What are the implications of going back to your previous regimen? Will it reduce ability of HAART to control HIV replication?

Response from Dr. Young

Hello thank you for posting from the Philippines.

As long as there has been no issues with virologic failure or drug resistance, there should be no problem switching from one medication to another and back again. Of course be mindful that switching to AZT may cause AZT-related side effects such as headache or nausea.

I hope that's helpful, and let us know how these medication switches turn out. BY



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