|Current status of Dolutegravir?
Mar 28, 2014
Hi Dr. Young. Could you tell me what the current status of Dolutegravir is? The last I heard it was in Phase III testing. I am currently using Isentress with no problems, but I understand that Dolutegravir is much more potent and less toxic. Will it be available soon?
| Response from Dr. Young
Dolutegravir (Tivicay) was FDA approved in the US last summer. In first-line therapy, Tivicay and Isentress performed identically (search for the Spring-2 study); in second-line treatment for people with drug resistant virus, Tivicay appears to be more potent virologically.
The toxicity profiles of the two drugs are very similar.
Hope that helps. BY
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