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Question about PEP (Post-exposure prophylaxis)

Mar 19, 2014

I may have been exposed to HIV in this this saturday when i had sex with a female frien of mine, then, about 10 hours later i went to my doctor and he gave me Post-exposure prophylaxis. My doctor prescribed to me Biovir (Zidovudina+Lamivudina)300+150 mg/ 2 caps twice a day and Lopinavir and ritonavir (Kaletra) 200+50 mg. I'm using these medications for 24 hours.

My question is the following: - In these respective drugs it is possible to contain HIV, like as vaccines, where the virus is attenuated?? - what these drugs will do?, How these drugs work?

I doubt very much that i might have caught HIV because i just recive an unprotect oral sex, I just took prophylaxis because I am a very suspicious men, could i say kind of paranoid. My fear now is get HIV or another disease from these drugs, there is this possibility?

Can I continue taking the medication even with 0% chance I have caught hiv Saturday?

I am very afraid of catching HIV, then if the "Kaletra and biovodir" have any chande to transmit hiv I'll stop taking it right now!

Response from Dr. Young

Hello and thank you for posting your question about PEP.

1) HIV medications do not contain the virus, so there is absolutely no way that you would receive the virus (attenuated or not) by taking the pills.

2) HIV medications work by stopping the virus from making copies of itself. In doing so, the meds prevent infection of cells. For more information about antiretroviral mediations, check out our Fact Sheet on

3) It's challenging to say zero risk, but based on your exposure and the fact that you're now taking PEP, I'd estimate your risk to be very, very low.

Hope that helps, BY

help me decide
I had sex with a prostitute for 10 mins and condom was broken from the top when finished.

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