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Stribild & Isentress

Mar 16, 2014

Hi there, For several years I have taken Atripla and Isentress and this combo has worked well for me (viral load fully suppressed after Atripla alone initially would not fully suppress it). My doctor and I have decided to switch to Stribild to help me get a good night's sleep (Atripla impacted my sleep). However, my doctor has prescribed me both Stribild and Isentress together and pharmacists and Gilead (Stribild) have suggested that I should not be taking Isentress with Stribild. Is it OK to continue both? Just would like second opinion. Thanks! Matt

Response from Dr. Young

Hello Matt and thanks for posting.

Since Stribild contains the integrase inhibitor elvitegravir and Isentress is another integrase inhibitor (raltegravir), there's no reason to take both together.

If your virus doesn't have a history of drug resistance, the Stribild alone is adequate.

I'd touch base with your doctor to confirm his or her intent.


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