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chenge kaletra to nevirapina

Nov 10, 2013

Hi doctor, Im using Kaletra, tenoforvir and lamivudine. But i m having problems with kaletra (diarrhea, triglicerideos e etc.. My dosctor give me two options nevirapina e foramprenavir(Lexiva). In your opinium change to nevirapina is good and safety? I have depression . So I cant use efavirenz . Do you think sangamo is more close to cure hiv ? thanks for help.

Response from Dr. Young

Hola and thanks for posting.

Assuming that you're on your first regimen (or more accurately, don't have any issues with viral drug resistance), switching from Kaletra to the NNRTI nevirapine should be ok and improve your diarrhea and triglycerides. It's important to monitor your liver health (by symptoms and lab tests after starting nevirapine, so make sure that this is part of your discussion with your doctor.

A switch to Lexiva (fosamprenavir), another protease inhibitor would only be expected to have modest improvements in your issues.

Regarding the Sangamo zinc-finger investigations, we're still quite a way off before we'll know if this results in meaningful treatments, never mind a "cure".

Abrazos, BY

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