Just how good of a drug is selzentry?
Nov 8, 2013
Hello Dr. Thank you for helping so many people. I have drug resistance and have had the test that would enable me to take selzentry. I am wondering why there are not many questions about it on here. I am thinking it is not used very much or only in salvage regimens. Could you please give me your personal opinion on what you think about this drug? Also, I see that it works on the immune system rather than the virus itself. That is a little confusing to me. Thank you!
Response from Dr. Young
Hello and thanks for posting.
Maraviroc (Selezentry) is a CCR5 co-receptor blocker that prevents HIV from entering cells. It's a very well tolerated and effective medication, as long as special HIV tests confirm that your virus uses this receptor. The medication prevents the binding of the virus to your CD4+ cells rather than inhibiting a viral enzyme.
It hasn't been used as much as other medications, primarily because of its twice-daily dosing, lack of co-formulation (compared with Atripla, Complera or Stribild) and requirement of CCR5 utilization. If you have a drug resistant virus and maraviroc provides one of the required 2 or 3 active medications, I'd have no reservation in using it.
Hope that helps, BY
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Night Sweats After Unprotected Vaginal Sex Sign Of HIV AIDS
- Swollen Lymph Glands After French Kissing Worried I Have HIV
- Vaginal Discharge After Oral Sex With No Protection Does It Mean I Have HIV
- How Long Does It Take To Get Genital Warts?
- Are Night Sweats A Sign Of Acute Hiv Infection?
- HIV Symptoms Rash Fever Headache Thrush Throat
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.