why not a 4 drug regimen to battle resistance
Aug 28, 2013
hi, in 2013 we already have plenty of different category molecules in hand with lesser side effects. why dont we try a 4 drug regimen instead of 3 drug haart to cut down the odds of emergence of resistance more confidently? for example, what if we use tenofovir+lamivudine+efavirenz + raltegravir regimen? another question is, from ur exerience how long atripla can work for a patient with full adherence before it fails due to resistance? regards.
Response from Dr. Young
Hello and thanks for posting.
You raise an interesting question-- one that was previously the question of a number of large randomized clinical trials. The answer was that there was no measurable benefit from using 4, instead of 3 drugs for HIV-- either from an effectiveness or drug resistance perspective.
Indeed, if anything, adding a 4th drug probably only increases cost and risk of toxicity.
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Chances Of Getting HIV From Having Sex During Period
- Chances Of Getting HIV From Sex With Sex Worker
- Probability Of Getting HIV From Cut On Hand
- Is Groin Pain A Symptom Of Acute HIV Infection?
- Is Testicular Pain An Acute Symptom Of HIV?
- Dizziness After Anal Sex Without Condom Does It Mean I Have HIV
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.