HIV Exposure Question about specific PEP regimen
Aug 11, 2013
Hello Doctors and all else offering advice. I Was exposed to HIV via non-receptive anal sex. The receiver tested positive because right after we had sex I freaked out and immediately purchased an Oraquick. (He didn't know). We then, within 2 hours were seen in the emergency room and i was given 300mg of viread and lamivudine. My perscription subsequently is 300mg of both each day for 30 days. however, I am worried after reading the internet that this regimen is too weak. As though i should be taking 3 different pills each day. Is this regimen good enough? should i go back to the emergency room and ask for a stronger prescription. Its been 24 hours since my exposure, and I have taken my second round of medication.
Response from Dr. Young
Hi and thanks for posting.
There's a bit of latitude in PEP regimens, indeed there are differences (IMO, non-important ones) between recommendations for post sexual and non-sexual exposure exposures.
Personally, in my opinion, think that for any significant exposure (sexual or othersiwse) that justifies PEP, that a three drug regimen should be used.
If initiated within 72 hours of exposure and adhered to, PEP is very effective; I'm not sure if the differences in 2 or 3 drugs actually mater, as there are few studies that adequately address the issue. What's much more important is to stay as adherent as possible to the regimen.
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