Aug 6, 2013
Is this true doctor? Is it true that is once a month injection treatment option? who will be able to use this ? Thanks in advance.
Response from Dr. Young
Hello and thanks for posting.
Nanoparticle formulation of HIV medications is under active investigation. If this works out, the formulation allows for very long acting injectable delivery of treatment.
One encouraging investigational drug is the integrase inhibitor S/GSK1265744 (744 for short). Very early results suggest that this formulation will allow for once- monthly (or even longer) dosing of this med. In one study in monkeys, once-monthly injection of 744 provided protective levels for pre-exposure prophylaxis (PrEP) against simian immunodeficiency virus. What is needed are additional long-acting formulations for treatment of chronically infected individuals.
So, who will benefit from nanoART? (I love your term) First, since PrEP is dependent of adherence to treatment, a once-monthly (or imagine, if you will, a every three month) treatment to prevent HIV would be a game changer. Second, chronically infected HIV+ people might benefit, but mostly if an entire regimen could be delivered as an infrequent injection. Groups are working on just such companion medications, including efforts with NNRTIs (non-nukes). New results on nanoparticle ART was presented at the IAS2013 meeting in Malaysia last month.
Stay tuned. I think that this will be a very exciting field in the months and years to come. BY
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Itchy Vagina After Condom Inside Out Sign Of HIV AIDS
- Purple Spots After Sex With Stripper Worried I Have HIV
- Tingling Lips After Licking Penis Worried I Have HIV
- White Tongue After Anal Sex Without Condom Does It Mean I Have HIV
- How Soon After Sex Can You Tell If You Contracted An Std?
- Is Dry Patches On My Penis A Sign Of Std?
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.