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body change
May 13, 2013

how come most people i see in zimbabwe on ART become darker and their faces develop bigger jaws. is it the type of drug they use or it happens to everyone. i recently started treatment (6 weeks and have been gaining weight).

Response from Dr. Young

Hello and thank you for posting from Zimbabwe.

Skin darkening is a characteristic side effect of the AZT (zidovudine) that is frequently prescribed for first-line treatment in many parts of Africa. Newer alternatives, such as tenofovir does not have this effect.

I'm not aware of the jaw enlargement that you've described.

I hope that is helpful, BY


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