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Switching from Efivarenz & Lamzid to Atripla
Mar 21, 2013

Can this switch be done? How do I go about it?

Response from Dr. Young

Hello and thanks for posting.

Yes, a switch from the twice-daily Lamzid (Combivir)+efavirenz to the once-daily Atripla (tenofovir/FTC/efavirenz) can be done.

It's important to make sure that one doesn't have pre-existing kidney injury or bone disease before switching, as the tenofovir component of Atripla itself is associated with these toxicities.

Once the decision to switch is made, then it's a simple mater of stopping the old regimen and starting the Atripla- no need to stop or take a break (indeed, it's better not to do so).

Hope that helps, BY



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