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Is Kaletra and Combivir the correct PEP

Mar 20, 2013

Hi, I was potentially, recently exposed to HIV and the ER prescribed Kaletra 200-50 3 tablets twice a day and Lamivudine- Zidovudine 1 tablet twice a day. That seems like a lot, but maybe that is correct? I wasn't sure how often ER docs see this type of thing. Nausea, diarrhea n heartburn have been at times, difficult side effect. What do you think?

Response from Dr. Young

Hi and thanks for posting.

While perhaps not the best tolerated regimens, Combivir (zidovudine/lamivudine) with Kaletra (lopinavir/ritonavir) is a very acceptable PEP regimen. More recent guidelines speak of using Truvada (tenofovir/FTC) with either a boosted PI or the HIV integrase inhibitor Isentress (raltegravir).

Either way, your on a potent PEP regimen and this is expected to dramatically reduce your risk of acquiring HIV.

Be well, BY

Truvada to Kivexa
Did I infect my nephew?

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