|Truvada to Kivexa
Mar 20, 2013
Hi Dr. Currently on Truvada + Viramune with great results except creatanine levels increasing from 0.9 - 1.26 mg/dl. The option is to change Truvada to Kivexa. Would Kivexa + Viramune be a workable comobo? I have taken Stocrin in the past but cannont tolerate it. thanks for your help
| Response from Dr. Young
Hello and thanks for posting.
Here in the US (and in many other parts of the world), a genetic test called HLA B5701 is recommended prior to the switch- as people who are positive for this genetic marker are at greater risk of allergic reaction to abacavir (part of Kivexa/Epzicom). If negative, then there's no risk. If this test is not available where you live, then monitoring for the allergic reaction is important- it's something we did successfully for many years before the advent of the HLA test.
I hope that helps. Let us know how the switch works out for you. BY
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