|switch from atripla to complera
Feb 21, 2013
Dear doctor,Because of sleep-and concentrationproblems my consultant would switch my treatment from atripla to complera. I am now 4 years witn atripla as first medicament. But now I have read that taking complera limits your later opcions to other regims based on a non-nucleoside. Is it not better to stay with atripla until a better opcion is available? Many thanks for answering.
| Response from Dr. Young
Hello and thanks for posting.
Switching to Complera would be reasonable, if the dietary requirement (taking the pill with a 400 cal meal) isn't a problem.
As for the resistance issues, people starting and subsequently experiencing treatment failure with Complera do typically have virus with a broader cross resistance problem than with other regimens. If you've been taking your Atripla without adherence problems and have been suppressed for 4 years, I'd doubt that this will be an issue for you.
There is indeed no reason to rush into a switch- you've been on your otherwise well-functioning regimen for a long time. Complera would allow you to continue on a one pill a day regimen; it might also be worth talking to your consultant about other regimens that might not be as low pill count, but still avoid the unwanted side effects.
Hope that helps, BY
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