|efivarenz and tenifover
Feb 15, 2013
can pregnant woman take efivarenz and tenifover
| Response from Dr. Young
Hello and thanks for posting.
First off, it's generally ok for pregnant women to continue taking successful HIV medications- even if it is efavirenz. There is some risk of birth defects in the first weeks of pregnancy from efavirenz, but yesterday's US (most conservative) DHHS treatment guidelines state:
The recommendation on use of efavirenz (EFV) during pregnancy was updated to be in accord with the recommendation in the Perinatal Antiretroviral Guidelines. The key update includes the following statement: "Because the risk of neural tube defects is restricted to the first 5 to 6 weeks of pregnancy and pregnancy is rarely recognized before 4 to 6 weeks of pregnancy, EFV can be continued in pregnant women receiving an EFV-based regimen who present for antenatal care in the first trimester, provided the regimen produces virologic suppression (CIII)."
Hope that helps, BY
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