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efivarenz and tenifover
Feb 15, 2013

can pregnant woman take efivarenz and tenifover

Response from Dr. Young

Hello and thanks for posting.

First off, it's generally ok for pregnant women to continue taking successful HIV medications- even if it is efavirenz. There is some risk of birth defects in the first weeks of pregnancy from efavirenz, but yesterday's US (most conservative) DHHS treatment guidelines state:

The recommendation on use of efavirenz (EFV) during pregnancy was updated to be in accord with the recommendation in the Perinatal Antiretroviral Guidelines. The key update includes the following statement: "Because the risk of neural tube defects is restricted to the first 5 to 6 weeks of pregnancy and pregnancy is rarely recognized before 4 to 6 weeks of pregnancy, EFV can be continued in pregnant women receiving an EFV-based regimen who present for antenatal care in the first trimester, provided the regimen produces virologic suppression (CIII)."

Hope that helps, BY



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