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Drug Interactions: Complera and MDMA

Feb 7, 2013

Would there be any harmful/deadly drug interaction between Complera and pure MDMA?

Response from Dr. Young

Hello,

I'd be very cautious about the use of Ecstacy (MDMA) and HIV medications especially those that are metabolized by the P450 cytochromes (like proteaseinhibitors, and to a lesser extent rilpivirine- part of Complera). There have been deaths reported in the literature from inadvertent overdoses due to drug-drug interactions.

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