|How much food with Stribild
Jan 29, 2013
I'm sorry if this question has been answered previously, but I could not find it on the site. My question is this...how much food do I need to eat when I take Stribild. I read the information from the manufacturer, but I am still not clear. It appears that the more food that is eaten, the more drug becomes available in the body. I'm really needing to lose some weight so I want to eat enough food but not more than necessary at one meal. More than anything, I want to do what is best to ensure that the drug is working at it's best.
Thank you in advance.
| Response from Dr. Young
Hi and thanks for posting.
It's recommended that Stribild (aka, Quad) be taken with food. The language from the manufacturer Gilead, is quite non-specific, though their studies show that taking Stribild with food increases the absorption of elvitegravir (one of the medications in the combo) significantly.
From the package insert: "with a light meal (~373 kcal, 20% fat) increased the mean systemic exposure of elvitegravir and tenofovir by 34% and 24%, respectively", compared to fasting, "the administration of single dose Stribild with a high fat meal (~ 800 kcal, 50% fat) increased the mean systemic exposure of elvitegravir and tenofovir by 87% and 23%, respectively."
If you're trying to loose weight, it's understandable that you don't want to ingest unnecessary calories or fat. Based on this data, it would seem that the first scenario (~375 calories and 20% fat) would be a reasonable target.
I hope that helps. BY
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