Re:How long we can alive in second line treatment
Jan 3, 2013
hello, i am a regular reader of this forum and found this question puzzling. first of all, Dr Young is absolutely right that second line can work for many many years, probably for 2 decades in some cases based on more than 95% adherence and avoidance of antacids(i hope i am not overestimating Dr BY!) then patient will go for next regimens based on isentress / maraviroc(based on tropism) or secong gen PI like darunavir. also there is good news about ibalizumab and many others (eg: some therapeutic vaccines) in the panel. so, dear friend, u still have to enjoy life for long long decades. but one thing i cant understand, why ur first regimen failed in just 3 years and 3 months? generally it should work for decades as well if adherence is >95%. Make sure that the reasons for ur switch is strong enough and discuss the case with expert like Dr BY and also please let us know as well. Dr BY, please tell me if i am wrong. anyway, a wonderful new year i wish for u all. voracious reader.
Response from Dr. Young
Hi Voracious Reader and thanks for sharing your thoughts.
To your question- sometimes people have regimen "failure" not because of drug resistance (or poor adherence), but because of side effects or toxicity. It's not clear from our previous poster as to the basis of the failure. In the case of drug resistance, we'll occasionally see this creep up in patients who didn't have the recommended baseline drug resistance testing and may have been placed unknowingly on an inadequately potent regimen.
But, if the regimen is thoughtfully selected, monitored and adhered to, drug resistance and virological failure is indeed very rare.
Hope that helps. Happy and healthy new year to you, BY
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Is It Possible To Get HIV From Genital Rubbing?
- Needle Stick How Long Does It Take To Test Positive For HIV
- Odds Of Infection Condom Slipped
- Chills After Unprotected Vaginal Sex Worried I Have HIV
- Painful Red Spots After Licking Vagina Worried I Have HIV
- Penis Discharge After Oral Sex Hooker What Are The Chances Of HIV
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.