|Trying Complera after rash due to Atripla
Dec 19, 2012
Almost 2 years ago, I started taking ATRIPLA (my CD4 were 360 at that point). On day 9, I had a skin rash, and my doctor told me to stop it. All this time, I had CD4 in the range of 500. Now, around 400, so I am about to start treatment on Complera. I know that only Sustiva is replaced in this regimen.
I am afraid of possibly getting the same allergy again. From your experience, is the Sustiva more connected to skin rashes or Tenofovir?
Thank you in advance
| Response from Dr. McGowan
Rilpivirine (which is the only new medicine in Complera that is not in Atripla)can cause a rash as well, but it is much less common than efavirenz. The two drugs belong to the same family - Non-nucleoside reverse transcriptase inhibitors. There are no studies yet on whether a person allergic to efavirenz would also be allergic to rilpivirine.
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