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Dec 4, 2012


I would like to commend your site and your efforts, as I am sure that your answers already helped many people. I was tested positive in August 2012, which was a big shock for me. Since then I'm on Truvada and Stocrin. My RNA fell from 1010 to UD in 3 weeks. My CD4 cells are 304 (28%). Like many others I have some issues with Stocrin. I noticed anxiety attacks that are becoming stronger every day. I was at my doctor who prescribed me Lexaurin (bromazepam) and Cipralex (Escitalopram), and refers me to a psychologist. My HIV doctor however advised me not to start Cipralex, because he wants me to replace Stocrin.

Do you suggest I should stay on Stocrin and Truvada and start taking antidepressants?

How long does it take to stop anxiety after stopping Stocrin?

Which combination of HAART do you suggest that will not have anxiety as a side effects (my doctor suggested Eviplera, but I read that this also causes axiety), (my bilirubin values are a little bit higher than are supposed to be)?

I look forward to your responses.

Response from Dr. Young


If you and your doctor agree that the efavirenz (Stocrin) could be contributing significantly to your anxiety, then it makes sense to consider switching off efavirenz to rilpivirine (in Epivlera/Complera) before starting medications to treat mood. (ie., why treat a side effect with another medication when switching might eliminate the problem altogether)

Mood symptoms with rilpivirine have been reported, but are far less common and less severe than those that I've seen with efavirenz.

Last, thanks for your kind words. I've been writing here at for over a decade; it's always fulfilling to know that the work helps people.

Hope that helps. Let us know how things turn out for you. BY

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