|switching from Etravirine to rilprivirine
Aug 24, 2012
HI Dr,i have been taking Truvada and Efavirenz for 3years but suffered a lot of bad dreams.My Dr recommended Etravarine as a replacement for Efavirence, I took Etraverine for 2months and i have gone completely depressed.Rilpiverine has been recommeded.Is this the right move for me since i have read that Rilpivirine is for patients who are starting HIV medication for the first time.
| Response from Dr. McGowan
As long as you have never had detectable viral load with drug resistance while on treatment, switching for toleravbility issues is generally safe. These 3 meds are all in the same family (non-nucleoside analog reverse transcripatase inhibitors, or NNRTIs for short). Usualy if efavirenz (the NNRTI in Atripla) works, the other 2 (etravirine and ripilvirine) should also work. Rilpivirine is generally well yolerated, can be once a day (in a single pill called Complera..similar to Atripla), but it must be taken with a full meal (400+ calories) and avoid with antacids. So, it may be an option. Be sure your viral load has remained undetectable with the switches made before changing again.
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