Switching form Viramune/Truvada to Isentress/Truvada
Aug 21, 2012
I've been diagnosed with HIV in Dec 2011. My CART started on 23 Jan 2012. CD4 count 55, VL 973000 copies/ml on start. After five weeks of therapy Viramune 2x200mg and Truvada 1x1 tbl(stricty adherent - no missed or delayed dose)CD4 coun and VL 83 and 86000 respectively. On 22 Apr 2012 my doctor switched my regimen to newly registerd Viramune XR 1x400mg instead of 2x200mg. After seven weeks from change I began feel myself slightly worse. On 26 Jun 2012 my CD4 count was 46 and VL 200000 copies. Blood samples for genotyping were taken and I've been switched to Truvada once daily and Isentress twice dail regimen. My main concern is bioavailability of Isentress. Manufacturer claims that the drug can be taken regardless of food, but truvada should be taken with food. Could you explain whether it could affect the absorption of Isentress? With best regards George
Response from Dr. Young
Hello George and thanks for posting.
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