Aug 11, 2012
dear experts, I have been put on PEP treatment following an unprotected oral sex episode with a shemale. The doctor has prescribed be Combivir, one tablet at 12 hours. Is this a good treatment scheme for PEP?
Response from Dr. Young
Hello and thanks for posting.
While you haven't described the details of your exposure (ie, if you were the insertive or receptive partner), oral sex carries a very low risk of HIV infection.
Combivir is part of recommended PEP regimens (and you're dosed correctly). Current guidelines usually recommend adding a so-called third agent (usually a protease inhibitor, though we use an integrase inhibitor too).
Given the lower risk nature of the exposure, the Combivir alone seems acceptable to me.
If you find yourself at ongoing risk, you might consider speaking to your doctor about pre-exposure prophylaxis (PrEP). We now have compelling evidence that PrEP can be very effective in reducing HIV rates in adherent patients.
I hope that helps and best of health to you, BY
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