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Truvada sparing regime

Aug 4, 2012

Does anyone care to comment on what a Truvada sparing regime looks like? What kind of side effects are common?

Response from Dr. Young

Hello and thanks for posting.

There are a variety of reasons why one might consider a regimen that does not include tenofovir (part of Truvada, Complera, Quad and Atripla)- these would include kidney or bone disease risks, or intolerance of the medication.

The most conservative alternative is to use a different NRTI, such as abacavir/3TC (Epzicom, Kivexa). Last month's hot off the press IAS-USA Guidelines suggest the use of tenofovir/FTC (Truvada) or abacavir/3TC as NRTI components of treatment. The later should be preceded by a genetic test, called HLA B5701, to determine if there's any risk of developing an allergic reaction. The medication is generally very well tolerated and not associated with kidney or bone problems.

For more information about recent treatment guidelines, take a look at our friend Dr. Melanie Thompson's interview with IFARA and TheBodyPro..

I hope that is helpful, BY

complera and clindamycin
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