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Norivir to 400mg Reyataz

Jul 11, 2012

HIV for 26 years and healthy! I have been on Norivir,Reyataz and Combivir for 4 years. Undetectable viral load, 560 t-cells and feel great except for a bloating feeling. My doctor suggested stopping the Norivir and increasing my Reyataz to 400mg. Any suggestions on the switch? Is this common in therapy? Can i ever go back on Norivir if I stop? Thank you for any advice!

Response from Dr. Young

Hello and thanks for posting.

Atazanavir (Reyataz) can either be dosed 300 mg with ritonavir (Norvir) or 400 mg without ritonavir. It's a reasonable to presume that some of your side effects could be related to the Norvir, so a simplification to unboosted atazanavir might help.

A number of my patients receive unboosted atazanavir (usually with abacavir/lamivudine), as studied in the ARIES clinical trial.

Should you need to in the future, this switch doesn't preclude going back to Norvir.

I hope that's helpful, BY

Efficacy/Synergy of Isentress+Norvir+Prezista+Viread
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