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Mutation vih and antibody detectable for elisa at six months

Feb 24, 2012

In the immune system can detect HIV mutations and generate antibodies detectable by ELISA at three and six months in 100% of the cases?

Response from Dr. McGowan

While we cannot say that a negative test at 6 months is 100% indicative that a person is not infected it is essentially true. Nothing in nature and science is 100%. There have been a few cases of late ser0-conversion reported, some in the setting where hepatitis C was simultaneously transmitted. The new Antigen-Antibody combo tests have virtually 100% sensitivity (in that if an infection is present in a sample, the test will be positive). So, especially if a person has tested negative on 2 or more occasions the likelihood of being truly negative is extremely high.



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