Feb 23, 2012
I have been taking Reyataz, Truvada, Norvir for 7 years . I'm resistant to Sustiva. Can I switch to this new once a day one pil Complera?
Response from Dr. Young
Hi and thanks for posting.
I'm slow to switch people off of successful regimens, especially ones like yours that remain part of the Preferred regimens on current US treatment guideliens.
What's at issue is the NNRTI resistance that you have- Complera includes the NNRTI rilpivirine. Depending on the extent of resistance (the type or number of resistance mutations) that your virus has to efavirenz (Sustiva) could make the switch ill advised. I'd speak to your doctor about the safety of such a switch.
Be well, BY
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