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New medication
Feb 21, 2012

Am currently using stavudine, stocrin and lamivudine. What will this be replaced with in the new medication of single doses a day?

Response from Dr. Young

Hello and thanks for posting.

Assuming that this is your first ARV regimen and you don't have any issues with viral load suppression, you're in luck.

First, efavirenz (Stocrin, Sustiva) and lamivudine (3TC, Epivir, or it's cousin drug FTC) can both be dosed once daily.

So, your question boils down to what to replace the twice daily (and now outdated) medication stavudine (d4T, Zerit) with. Current treatment guidelines would suggest using tenofovir (Viread, available as a coformulation with FTC and efavirenz); if you have kidney or bone problems, then an alternative to tenofovir would be abacavir (Ziagen, available coformulated with 3TC-called Kivexa/Epzicom).

The combination of tenofovir/FTC/efavirenz is commonly prescribed as Atripla (you can find much about this medication on these pages). Both combinations are parts of the current US treatment guidelines.

Which medication combo is best for you depends on your specific medical history and what is available in your country.

I hope that's helpful. BY



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