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CD8 significance
Feb 4, 2012

I understand that HIV infection generally makes CD4 counts decline and CD8 counts increase. With successful treatment this trend reverses, i.e. the ratio of CD4 to CD8 increases. Normal is between 1 and 6. Looking at my results over the past 5 tests (18 months)my CD4 has gone from 796 to 1006, yet my CD8 has gone from 774 to 1174. A steady ratio of about 1. My doctor is not concerned, but it leaves me curious. Why hasn't my CD8 count decreased? Any insights?

Response from Dr. Young

Hello and thanks for posting.

I'm with your doctor. Your overall results, especially your CD4 count and CD4/CD8 ratio are all in the normal range.

BTW, I'd double check your normal ranges for the ratio- I'm happy if my patients are anywhere near 1.0.

Be well, BY



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