Why not Epzicom instead of Ziagen and Epivir
Sep 21, 2011
A Spanish fiend om mine who's recently been diagnosed as hiv-positive, has been put on a regiment of darunavir 800mg + ritonavir 100mg + 2 tablets of abacavir (600mg) + 250mg of lamivudine in liquid form. He complains about having to take the liquid, which is horrible and because of that is less therapy adherent than he should be. I wonder why he cant just take the Epzicom combo, which only contains 50mg more lamivudine. He is a kidney patient and on dialysis 3 times a day. His doctor claamis that 300mg would be too much for him, but as i see it, having to take the liquid is doing more harm than good. Can you sort this out?
Response from Dr. Young
Hola and thanks for posting.
I can tell you why the Spanish doctors have started your friend specifically on the liquid+pill versions of his medications. One possibility is that your friend is quite small or perhaps has poor kidney function (both could require a separated dose of the abacavir (Ziagen) and lamivudine (Epivir). It could be also what's in stock; it is sometimes the case that the doctors (I hear this particularly from Europe) won't start the coformulated medication (such as Epzicom/Kivex) until it's clear that the patients tolerate all parts of the pill.
Hope that helps. Please feel free to write back if you have any other questions. BY
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