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Aug 14, 2011

I am currently taking Kaletra and Combivir as PEP for a serious exposure to a heroine user. My question (I have several. But the one I suspect you can answer) is that one of these two meds gives me a serious case of diarhea (absolute squirts...) about an hour after taking them. Is that likely to cause these meds to not be absorbed into my blood stream (from first dose on)? Is there anything you can recommend to treat that (I'm not that "inconvenienced", I'm just worried about absorption)

Response from Dr. Young

Hello and thanks for your post.

Sorry to hear about your situation.

Kaletra (lopinavir/ritonavir) is often associated with diarrhea. If you don't see the actual pills in your stool (yuk, I know), you've more than likely absorbed the medication.

Taking the medications with food in your stomach can often help with the trots, and as long as there's no reason to suspect any other cause of the diarrhea, anti-diarrheal medications, like over-the-counter Immodium, can slow things down to a bearable pace.

Best of health, BY

HIV Meds & Supplements
bromelain and arvi

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