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Reason to change meds

Jul 28, 2011

I have been on Combivir and Nevirapine since 2003 when I was diagnosed. My viral load is always undetectable and the only side effect I know of is a slight elevation in cholesterol. What would be the benefit of changing to a newer regimen?

Response from Dr. McGowan

In your case the only reason to change would be if you were having a side effect or for convenience (fewer pills or once a day dosing). Nevirapine is very cholesterol friendly so that is not a reason to change. The zidovudine in Combivir can cause some effects on the muscles, blood counts (anemia) and fat. If you are afraid of these effects or have any signs of these changes it might be reasonable to look at other options. Otherwise you may opt keep things as they are. It is always a good idea to look at your options as new treatments come out and see if there may be an advantages...doesn't mean you have to switch.

Best, Joe

CD4 stil declining after 1st month of treatment

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