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Truvada & Isentress

Apr 17, 2011

Hi Dr. Young, I'll make this quick. Do you expect to see Isentress & Truvada become available for once a day dosing like Atripla in the near future? Thank you.

Response from Dr. Young

Hello and thanks for your post.

Unfortunately, once-daily raltegravir (ISENTRESS) was found in the QDMRK study to not be as effective as twice-daily-- for this reason, the Truvada+Isentress regimen won't be once-daily.

There are other once-daily integrase inhibitors (namely elvitegravir and dolutegravir) that are in development. If these programs successfully conclude with regulatory agency approval, then we could see an entirely once-daily integrase-containing regimen.

Hope this helps, BY

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