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missed dose two days in a row
Oct 4, 2010

hello,

i was diagnosed just over a year ago and was quickly put on epzicom, prezista, and norvir. my vl has been either undetectable or <90 since January 2010.

I have been 100% adherent, but realized this morning I had missed the last two days in a row. (I recently changed jobs so my routine changed slightly. I packed my pillboxes for work, but forgot to actually take them).

I called my dr. this morning and his nurse said to just start taking them normally today and make sure not to miss anymore.

would a two day lapse like I just had nomally cause long term harm?

thanks so much for your input.

Response from Dr. McGowan

Thanks for your question. Many people have a similar experience.

The good news is that since your viral load has been fully suppressed for so long missing a couple of doses should not make much difference as long as you start right back. It may take the virus a few days to "wake up" after the meds get out of your bloodstream. So restarting right away will prevent that.

It is a different situiation if the missed doses happen early on before the virus is undectable or if you regularly miss doses- that is much more risky for letting drug resistance develop because the virus is growing when the level of meds in the blood is too low.

Best, Joe



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