Aug 29, 2010
my son is taking kaletra,videx and stavudine. which is the best combination to move to. i am taking videx, stavudine and stocrin and which is the option to move to. at present the combinations are working well. please may you help
Response from Dr. Young
Hello and thanks for your post.
From the sounds of your question, you don't live in the US but somewhere else where treatment options might not be the same as we have here (or in Europe).
In short, the combination of Videx (ddI) and Zerit (d4T, stavudine) is no longer recommended because of significantly increased risk of lipodystrophy, pancreatitis and neuropathy. The use of the combination could be supported for second line use if no other alternative was available.
So, the answer to your question depends much on if these represent first-line or other lines of treatment, what type of drug resistance you might have and what available treatment options exist in your country. Is your son currently experiencing failure of the Kaletra/ddI/d4T regimen? What previous treatments did he receive?
I hope this helps, please write back with additional details, BY
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