The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App 
Professionals >> Visit The Body PROThe Body en Espanol
Ask the Experts About

Choosing Your MedsChoosing Your Meds
Rollover images to visit our other forums!
Recent AnswersAsk a Question
  • Email Email
  • Glossary Glossary

Change in Treatment (new med Kivexa)

Jul 30, 2010

Dear Doctor,

I have beentaking for more that ten years Stocrina dn Combivir, a month ago after discussing with my doctor we decided to chante combivir for Kivexa, started taking it and all good, three weeks after starting, I have experiences stomac pains (on and off) sometimes light sometimes very painful, question is: How long does it take for the body to get used to kivexa? As i ws reading the side effects it says "usually effects disapear with time". It has been two weeks since I have experienced the pains, should I worry or wait for some more time before I go back to my doc? I do take buscopon for the pains how long can I take buscopon for?. Many thanks and best regards

Response from Dr. McGowan

Thanks for your post.

Kivexa (abacavir + lamivudine aka Epzicom) can be associated with a hypersensitivity reaction. Specifically the abacavir component (also included in meds such as ziagen and trizivir). Symptoms can start within the first 2 weeks usually and get progressively worse with each dose. Abdominal pain may be one of these effects. Fever, cough, rash may also be seen. A blood test (called an HLA B5701 screen) is often done before a person is prescribed abacavir to help reduce the chances of these reactions. People who screen HLAB5701 negative are much much less likely to have these reactions.

It is very very important to let your doctor know about these symptoms...if it is a reaction to abacavir it can get worse and can become severe. Especially if you stop the medicine DO NOT restart it without discussing with your doctor. Restarting abacavir after a reaction can cause a much worse (hypersensitive) effect and has even caused death in rare cases.

Hope things work out well,


Time Chang and Changing Meds
Why is genotype testing required for treatment naive patients?

  • Email Email
  • Glossary Glossary

 Get Email Notifications When This Forum Updates or Subscribe With RSS



This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.

Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.

Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint