|Help Choosing Meds
Apr 30, 2010
I have been positive for 9 years and on meds for only 4 of those years. For the last 4 years my CD4's have gotten to 14 and I'm off meds again. My main problem other than side effects is dosing. I can only take meds once a day and can not guarantee that I can take with food. Is there anything other than Atripla/Sustiva that I can take with Truvada that can effectively be taken once daily without food. I have no resistance to anything and luckily have not ever been sick but I am getting scared. I recently had boosted Reyataz with Truvada that worked wonders in 4 months then just stayed the same for the next 18 months. I yellowed, had stomach problems, a kidney stone (Reyataz), and couldn't always take with food. What can I do and is there anything out there for me? I just feel like giving up. Please advise if you can. Thank you. Michael
| Response from Dr. McGowan
As long as there is no drug resistance there are possibilities for you. Truvada can be given once a day with Prezista and norvir, like Reyataz it is usually given with food but could be on an empty stomach. If the Norvir is a problem, since your CD4 count is 14 you could take viramune (starts as 200 mg once a day for 2 weeks then 400 mg once a day). The once a day dosing has been effective in studies, although it is not in the official dose recommendations. Isentress is another medication that is recommended as a twice daily med but is now being studied once a day (800 mg). This might be an option if the study results are good.
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