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Dr McGowan (HIV med help)
Jan 28, 2010

I took a course of PEP and had a negative 3 month test. Does PEP delay antibody production?

Response from Dr. McGowan

Thanks for your question.

It is generally recommended to get an HIV test at 6 months after exposure. Less than 1% of people will convert after 6 months so it is very rare. It is not known if using PEP would lead to a delayed conversion. There have been cases of delayed conversion have been when hepatitis C was also transmitted at the same time. Since it is such a rare event to convert after 6 months it is not known if PEP would be an issue. A person may elect to test at 1 year if they were very concerned about this very low risk.

Joe



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