Jan 22, 2010
Dear doctor my question is why can't companies come together and combine the drugs which is commonly used eg; Atazanavir+norvir+Tenofovir+FTC, AZT+3TC+Lopinavir+Ritonavir, Etravirine+Darunavir+Ritonavir+Raltegravir, etc
Response from Dr. Young
Hello and thanks for your provocative question.
The basic answer is that companies are often reluctant to collaborate to develop fixed-dose combinations of medications when it requires medications from different companies. Indeed, the only multi-company, multi-drug combination is Atripla. All of the combos that you've listed would require the joint venture of three or more companies; a very unlikely event. Some combos are of interest, to be sure, but there are many contractual and financial barriers.
So, until all of the candidate meds become generic, having list of combinations as fixed-dose combination pills will be quite unlikely.
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