Atripla exposed high / low temperature during travel. Is it safe?
May 17, 2009
I've just came back from traveling to a tropical country and had taken two boxes of Atripla with me. One - opened, was always safe with me, stored in reasonable temperatures.
The other box, unopened, was stored in a main luggage, which has been exposed to a direct tropical sunlight for around two days (temperature in the shadow 35 C). Luggage was probably heated up quite badly. Unfortunately - later on, I stayed in an unconditioned room and stored the very same box in the fridge, which later on appeared to literally freeze fruits stored in it, therefore I think I've accidentally exposed the same box of pills for temperature of around 0 degrees Celsius for over 72 hours.
As soon as I got access to the internet I have checked storage guidelines for Atripla and they mention that it should not be stored in temps below 15 and above 30 degrees.
Is there a risk that such an exposure may have lower the effectiveness of Atripla and can it create a risk for me?
I have only 3 safely stored tablets left, and then have to either get a new box or start the one exposed to high / low temps.
Please help... Thank you so much in advance!
Response from Dr. McGowan
You are correct that the package insert states that Atripla is best stored at 25 degrees C (or 77F) with "excursions permitted to 1530 C (5986 F)." So based on the information you provided, one could not reliably vouch for the potency of the medication you have and starting a new bottle would be a reasonable conclusion.
Get Email Notifications When This Forum Updates or Subscribe With RSS
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.