May 14, 2009
Response from Dr. McGowan
There are no significant drug interactions, so in that sense it would be OK. This particular combination has not been tested in a clinical trial.
The real answer depends on the level of drug resistance that is present in your virus. There must be 3 active drugs in the combination in order for it to work (sometimes you can get away with 2 if one of them has a high barrier to resistance like a "boosted" protease inhibitor...which means one combined with ritonavir to increase it's blood levels). So you need to discuss this with your health care provider to be sure that this combo would provide at least 3 active drugs based on your past treatment, and evidence of resistance on testing of your virus.
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